Short description of project
Some drug molecules such as anthocyanidins and vitamin B1 have inherent stability issue and this affects their storage and absorption. An effective means of drug formulation to improve stability and bioavailability of these drugs is highly desired. In this proposed project, we intend to employ a novel synthetic macrocyclic molecule named Cucurbituril to encapsulate and formulate with these drugs, and investigate the host molecule’s protective effect regarding the physiochemical stability of these guests. In addition, the encapsulation's effect on bioactivities of these drugs will be evaluated as well.
Information of Offered Internship
Level of Internship Hours per Month
Level 1 - 40 hours
Commencement Month
June
Duration
6 Months
Internship requirements: i.e. work, practice and training
The internship will involve hands-on training of some basic chemistry related laboratory research work, for instance, preparation of solutions, and analytical measurements by the use of state-of-the-art research facility such as UV-Vis, and Fluorescent spectrometers, Mass spectrometry, NMR. With hands-on training done, the intern will be expected to conduct the proposed research work with limited supervision. An ideal candidate should fulfill the following requirements:
1) A biomedical sciences major or other natural sciences or engineering major
2) Being keen to learn new techniques in the area of pharmaceutical sciences
3) Interested in science and laboratory work
4) Excellent communication skills including writing in English and presentation
5) Being independent and a team player
1) A biomedical sciences major or other natural sciences or engineering major
2) Being keen to learn new techniques in the area of pharmaceutical sciences
3) Interested in science and laboratory work
4) Excellent communication skills including writing in English and presentation
5) Being independent and a team player